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1

Crystal Structure of the Human Cannabinoid Receptor CB1

Hua, Tian, Vemuri, Kiran, Pu, Mengchen, Qu, Lu, Han, Gye Won, Wu, Yiran, Zhao, Suwen, Shui, Wenqing, Li, Shanshan, Korde, Anisha, Laprairie, Robert B., Stahl, Edward L., Ho, Jo-Hao, Zvonok, Nikolai, Z

Journal:

Year:

2016

Language:

english

File:

PDF, 6.67 MB

english, 2016

2

Self-medication of a cannabinoid CB2 agonist in an animal model of neuropathic pain

Tannia Gutierrez, Jonathon D. Crystal, Alexander M. Zvonok, Alexandros Makriyannis, Andrea G. Hohmann

Journal:

Year:

2011

Language:

english

File:

PDF, 1.13 MB

english, 2011

3

Synthesis of 2-aryl-1,5-dihydro-1-azapyrene derivatives

Journal:

Chemistry of Heterocyclic Compounds

Year:

1995

Language:

english

File:

PDF, 107 KB

english, 1995

4

The first reliable record of fossil leatherback sea turtle (Dermochelyidae) in northern Eurasia (Middle Eocene of Ukraine)

Zvonok, E. A., Danilov, I. G., Syromyatnikova, E. V.

Journal:

Paleontological Journal

Year:

2013

Language:

english

File:

PDF, 965 KB

english, 2013

5

Recyclization of spiro[3a-Hydroxypiperidin-4,2′-oxiranes] in basic medium

A. M. Zvonok, E. B. Okaev

Journal:

Chemistry of Heterocyclic Compounds

Year:

1994

Language:

english

File:

PDF, 298 KB

english, 1994

6

Antinociceptive Effects of Racemic AM1241 and Its Chirally Synthesized Enantiomers: Lack of Dependence upon Opioid Receptor Activation

Elizabeth J. Rahn, Alexander M. Zvonok, Alexandros Makriyannis, Andrea G. Hohmann

Journal:

The AAPS Journal

Year:

2010

Language:

english

File:

PDF, 565 KB

english, 2010

7

ChemInform Abstract: Reaction of β-Arylacryloyloxiranes with Phenylhydrazine.

N. M. KUZ'MENOK, A. M. ZVONOK

Journal:

Year:

1996

File:

PDF, 28 KB

1996

8

Synthesis of epoxycarbonyl pyrroline derivatives by cycloaddition of benzonitriliop-nitrophenyl-methanide toα,β-unsaturated epoxy ketones

A. M. Zvonok, V. Librando, E. B. Okaev, S. G. Mikhalyonok

Journal:

Chemistry of Heterocyclic Compounds

Year:

1998

Language:

english

File:

PDF, 253 KB

english, 1998

9

Immunofluorescent spectral analysis reveals the intrathecal cannabinoid agonist, AM1241, produces spinal anti-inflammatory cytokine responses in neuropathic rats exhibiting relief from allodynia

Jenny L. Wilkerson, Katherine R. Gentry, Ellen C. Dengler, James A. Wallace, Audra A. Kerwin, Megan N. Kuhn, Alexander M. Zvonok, Ganesh A. Thakur, Alexandros Makriyannis, Erin D. Milligan

Journal:

Brain and Behavior

Year:

2012

Language:

english

File:

PDF, 2.09 MB

english, 2012

10

ChemInform Abstract: Synthesis and Chemical Transformations of 5-Hydroxy-4-oxo-3-arylpyrrolidino(1,2-b)pyrazoles.

ZVONOK, A. M., KUZ'MENOK, N. M., STANISHEVSKII, L. S.

Journal:

Year:

1990

File:

PDF, 175 KB

1990

11

272 Self-administration of a cannabinoid CB2 agonist in an animal model of neuropathic pain

T. Gutierrez, J.D. Crystal, K.W. Maxwell, A.M. Zvonok, A. Makriyannis, A.G. Hohmann

Journal:

European Journal of Pain

Year:

2007

Language:

english

File:

PDF, 38 KB

english, 2007

12

Activation of peripheral cannabinoid CB1 and CB2 receptors suppresses the maintenance of inflammatory nociception: a comparative analysis

T Gutierrez, J N Farthing, A M Zvonok, A Makriyannis, A G Hohmann

Journal:

British Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 175 KB

english, 2007

13

On a tomistomine crocodile (Crocodylidae, Tomistominae) from the Middle Eocene of Ukraine

E. A. Zvonok, P. P. Skutschas

Journal:

Paleontological Journal

Year:

2011

Language:

english

File:

PDF, 531 KB

english, 2011

14

The cannabinoid CB 2 receptor agonist AM1241 enhances neurogenesis in GFAP/Gp120 transgenic mice displaying deficits in neurogenesis

Avraham, Hava Karsenty, Jiang, Shuxian, Fu, Yigong, Rockenstein, Edward, Makriyannis, Alexandros, Zvonok, Alexander, Masliah, Eliezer, Avraham, Shalom

Journal:

British Journal of Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.99 MB

english, 2014

15

Mass Spectrometric Characterization of Human N -Acylethanolamine-hydrolyzing Acid Amidase

West, Jay M., Zvonok, Nikolai, Whitten, Kyle M., Wood, JodiAnne T., Makriyannis, Alexandros

Journal:

Journal of Proteome Research

Year:

2012

Language:

english

File:

PDF, 2.88 MB

english, 2012

16

Synthesis of 5-Hydroxy- and 5-Amino-1-tosyl-5-phenyl-3-(2-arylvinyl)-4,5-dihydropyrazoles.

Nina M. Kuz'menok, Tatyana A. Koval'chuk, Alexander M. Zvonok

Journal:

Year:

2005

File:

PDF, 14 KB

2005

17

Synthesis and stereochemistry of 1-alkyl-2-aryl-3-(2-methyl-2,3-epoxypropionyl) aziridines

A. M. Zvonok, N. M. Kuz'menok, L. S. Stanishevskii

Journal:

Chemistry of Heterocyclic Compounds

Year:

1980

Language:

english

File:

PDF, 235 KB

english, 1980

18

AM2389, a high-affinity, in vivo potent CB1-receptor-selective cannabinergic ligand as evidenced by drug discrimination in rats and hypothermia testing in mice

Torbjörn U. C. Järbe, Sherrica Tai, Brian J. LeMay, Spyros P. Nikas, Vidyanand G. Shukla, Alexander Zvonok, Alexandros Makriyannis

Journal:

Psychopharmacology

Year:

2012

Language:

english

File:

PDF, 529 KB

english, 2012

19

ChemInform Abstract: Stereospecificity of the Rearrangement of Spiro(3-hydroxypiperidine-4, 2′-oxirane)s under Action of Methylmagnesium Iodide.

A. M. ZVONOK, E. V. OKAEV

Journal:

Year:

1995

File:

PDF, 28 KB

1995

20

Synthesis and pharmacological properties of certain 3,4-dihydroxypiperidines

L. S. Stanishevskii, A. S. Zakharevskii, A. M. Zvonok, E. V. Yushkevich, L. A. Melentovich, A. P. Lugovskii

Journal:

Pharmaceutical Chemistry Journal

Year:

1990

Language:

english

File:

PDF, 452 KB

english, 1990

21

Mass Spectrometry-based Proteomics of Human Cannabinoid Receptor 2: Covalent Cysteine 6.47(257)-Ligand Interaction Affording Megagonist Receptor Activation

Szymanski, Dennis W., Papanastasiou, Malvina, Melchior, Katja, Zvonok, Nikolai, Mercier, Richard W., Janero, David R., Thakur, Ganesh A., Cha, Sangwon, Wu, Billy, Karger, Barry

Journal:

Journal of Proteome Research

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

22

The Mechanism of the Disintegration of Phospholipid Membranes with Human Monoacylglycerol Lipase (hMGL)

Silin, Vitalii I., Karageorgos, Ioannis, Vanderah, David J., Zvonok, Nikolai, Marino, John, Makriyannis, Alexandros

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 65 KB

english, 2015

23

ChemInform Abstract: Synthesis of 1,2,3,4-Tetrahydropyridin-4-ones by Heterocyclization of β-Amino-β-arylacryloyloxiranes.

ZVONOK, A. M., KUZ'MENOK, N. M., KORSHUN, V. A., STANISHEVSKII, L. S.

Journal:

Year:

1989

File:

PDF, 123 KB

1989

24

Synthesis of 3-aryl-5-methylpyrrolidino[1,2 b]pyrazoles

N. M. Kuz'menok, A. M. Zvonok

Journal:

Chemistry of Heterocyclic Compounds

Year:

1994

Language:

english

File:

PDF, 251 KB

english, 1994

25

Middle Eocene Pelagornithidae and Gaviiformes (Aves) from the Ukrainian Paratethys

GERALD MAYR, EVGENIJ ZVONOK

Journal:

Year:

2011

Language:

english

File:

PDF, 805 KB

english, 2011

26

Construction of versatile Escherichia coli-yeast shuttle vectors for promoter testing in Saccharomyces cerevisiae

Zvonok, Nikolai M., Horv'ath, Éva, Bajszár, György

Journal:

Year:

1988

Language:

english

File:

PDF, 543 KB

english, 1988

27

Specific Inter-residue Interactions as Determinants of Human Monoacylglycerol Lipase Catalytic Competency

Tyukhtenko, Sergiy, Karageorgos, Ioannis, Rajarshi, Girija, Zvonok, Nikolai, Pavlopoulos, Spiro, Janero, David R., Makriyannis, Alexandros

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 2.05 MB

english, 2016

28

ChemInform Abstract: Reaction of β-Arylacryloyloxiranes with Phenyl Azide. Synthesis and Chemical Transformations of β-Phenylamino-β-arylacryloyloxiranes.

ZVONOK, A. M., KUZ'MENOK, N. M., STANISHEVSKII, L. S.

Journal:

Year:

1989

File:

PDF, 197 KB

1989

29

Synthesis of azetidin-3-ones by heterocyclization of α-cyclohexylamino-α′,Β′-epoxy ketones

A. M. Zvonok, N. M. Kuz'menok, L. S. Stanishevskii

Journal:

Chemistry of Heterocyclic Compounds

Year:

1988

Language:

english

File:

PDF, 434 KB

english, 1988

30

ChemInform Abstract: Recyclization of Spiro(3α-hydroxypiperidine-4,2′-oxiranes) in Alkaline Medium.

A. M. ZVONOK, E. B. OKAEV

Journal:

Year:

1995

File:

PDF, 29 KB

1995

31

Remains of sea turtles from the Ikovo locality (Lugansk Region, Ukraine; Middle Eocene)

Zvonok, E. A., Danilov, I. G., Syromyatnikova, E. V., Udovichenko, N. I.

Journal:

Paleontological Journal

Year:

2013

Language:

english

File:

PDF, 1.11 MB

english, 2013

32

On the stereospecificity of the rearrangement of spiro[3-hydroxypiperidine-4,2′-oxiranes] by the action of methylmagnesium iodide

A. M. Zvonok, E. V. Okaev

Journal:

Chemistry of Heterocyclic Compounds

Year:

1994

Language:

english

File:

PDF, 108 KB

english, 1994

33

Reaction of 1-alkyl-2-aryl-3-(2-methyl-2,3-epoxypropionyl)aziridines with boron trifluoride etherate in methanol

A. M. Zvonok, N. M. Kuz'menok, I. G. Tishchenko

Journal:

Chemistry of Heterocyclic Compounds

Year:

1986

Language:

english

File:

PDF, 444 KB

english, 1986

34

Administration of AM 1241, a cannabinoid 2 (CB2) receptor selective agonist, to the rodent spinal cord reverses Chronic Constriction Injury (CCI) induced allodynia

J. Wilkerson, E. Dengler, G. Thakur, J. Wallace, A. Zvonok, A. Makriyannis, J. Ashton, E. Milligan

Journal:

The Journal of Pain

Year:

2009

Language:

english

File:

PDF, 39 KB

english, 2009

35

Synthesis and evaluation of potent and selective MGL inhibitors as a glaucoma treatment

Alapafuja, Shakiru O., Malamas, Michael S., Shukla, Vidya, Zvonok, Alexander, Miller, Sally, Daily, Laura, Rajarshi, Girija, Miyabe, Christina Yume, Chandrashekhar, Honrao, Wood, JodiAnne, Tyukhtenko,

Journal:

Bioorganic & Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.13 MB

english, 2018

36

Synthesis and stereochemistry of α,β,α′,β′-diepoxy ketones

L. S. Stanishevskii, I. G. Tishchenko, A. M. Zvonok, N. M. Kuz'menok

Journal:

Chemistry of Heterocyclic Compounds

Year:

1983

Language:

english

File:

PDF, 461 KB

english, 1983

37

Synthesis of the diastereomeric 2-aryl-1-cyclohexyl-3-(2,3-epoxypropionyl)aziridines

A. M. Zvonok, N. M. Kuz'menok, L. S. Stanishevskii

Journal:

Chemistry of Heterocyclic Compounds

Year:

1986

Language:

english

File:

PDF, 338 KB

english, 1986

38

Selective Activation of Cannabinoid CB2 Receptors Suppresses Neuropathic Nociception Induced by Treatment with the Chemotherapeutic Agent Paclitaxel in Rats

Rahn, E. J., Zvonok, A. M., Thakur, G. A., Khanolkar, A. D., Makriyannis, A., Hohmann, A. G.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2008

Language:

english

File:

PDF, 333 KB

english, 2008

39

Functional selectivity at G-protein coupled receptors: Advancing cannabinoid receptors as drug targets

Mallipeddi, Srikrishnan, Janero, David R., Zvonok, Nikolai, Makriyannis, Alexandros

Journal:

Biochemical Pharmacology

Year:

2016

Language:

english

File:

PDF, 596 KB

english, 2016

40

ChemInform Abstract: Synthese und einige chemische Umwandlungen von 4′-Aryl-4-hydroxy-4-methyl- 4,5,4′,5′-tetrahydro- und 4,5-Dihydro-3,3′-bipyrazolen.

ZVONOK, A. M., KUZ'MENOK, N. M., TISHENKO, I. G., STANISHEVSKII, L. S.

Journal:

Chemischer Informationsdienst

Year:

1984

File:

PDF, 204 KB

1984

41

ChemInform Abstract: Reaction of 1-Alkyl-2-aryl-3-(2-methyl-2,3-epoxypropionyl)aziridines with Boron Trifluoride Etherate in Methanolic Solution.

ZVONOK, A. M., KUZ'MENOK, N. M., TISHCHENKO, I. G.

Journal:

Chemischer Informationsdienst

Year:

1986

File:

PDF, 192 KB

1986

42

ChemInform Abstract: STEREOCHEMISTRY OF THE REACTION OF 3-HYDROXY-4-PIPERIDONES WITH ORGANOMETALLIC COMPOUNDS

ZVONOK, A. M., LUGOVSKII, A. P., MASHENKOV, V. A., STANISHEVSKII, L. S.

Journal:

Chemischer Informationsdienst

Year:

1983

Language:

german

File:

PDF, 239 KB

german, 1983

43

Metabolic Profiling of a CB2 Agonist, AM9338, Using LC-MS and Microcoil-NMR: Identification of a Novel Dihydroxy Adamantyl Metabolite

Honrao, Chandrashekhar, Ma, Xiaoyu, Kulkarni, Shashank, Joshi, Vinit, Malamas, Michael, Zvonok, Alexander, Wood, JodiAnne, Strand, David, Guo, Jason J., Makriyannis, Alexandros

Journal:

Frontiers in Pharmacology

Year:

2020

File:

PDF, 1.98 MB

2020

44

Comprehensive Proteomic Mass Spectrometric Characterization of Human Cannabinoid CB2 Receptor

Zvonok, Nikolai, Yaddanapudi, Suma, Williams, John, Dai, Shujia, Dong, Keling, Rejtar, Tomas, Karger, Barry L., Makriyannis, Alexandros

Journal:

Journal of Proteome Research

Year:

2007

Language:

english

File:

PDF, 385 KB

english, 2007

45

Characterization of fluoroquinolone-resistant mutant strains of Mycobacterium tuberculosis selected in the laboratory and isolated from patients

Alangaden, G. J., Manavathu, E. K., Vakulenko, S. B., Zvonok, N. M., Lerner, S. A.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1995

Language:

english

File:

PDF, 257 KB

english, 1995

46

ChemInform Abstract: SYNTHESIS AND STEREOCHEMISTRY OF 1-ALKYL-2-ARYL-3-(2-METHYL-2,3-EPOXYPROPIONYL)-AZIRIDINES

ZVONOK, A. M., KUZ'MENOK, N. M., STANISHEVSKII, L. S.

Journal:

Chemischer Informationsdienst

Year:

1980

File:

PDF, 105 KB

1980

47

ChemInform Abstract: SYNTHESIS AND STEREOCHEMISTRY OF α,β,α′,β′-DIEPOXYKETONES

STANISHEVSKII, L. S., TISHCHENKO, I. G., ZVONOK, A. M., KUZ'MENOK N, M.

Journal:

Chemischer Informationsdienst

Year:

1983

File:

PDF, 128 KB

1983

48

Covalent Inhibitors of Human Monoacylglycerol Lipase: Ligand-Assisted Characterization of the Catalytic Site by Mass Spectrometry and Mutational Analysis

Nikolai Zvonok, Lakshmipathi Pandarinathan, John Williams, Meghan Johnston, Ioannis Karageorgos, David R. Janero, Srinivasan C. Krishnan, Alexandros Makriyannis

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 1.33 MB

english, 2008

49

Crystal Structure of the Human Cannabinoid Receptor CB2

Li, Xiaoting, Hua, Tian, Vemuri, Kiran, Ho, Jo-Hao, Wu, Yiran, Wu, Lijie, Popov, Petr, Benchama, Othman, Zvonok, Nikolai, Locke, K’ara, Qu, Lu, Han, Gye Won, Iyer, Malliga R., Cinar, Resat, Coffey, Na

Journal:

Year:

2019

Language:

english

File:

PDF, 5.67 MB

english, 2019

50

276 Selective activation of cannabinoid CB2 receptors suppresses chemotherapeutic neuropathy evoked by paclitaxel and vincristine administration

A.G. Hohmann, E.J. Rahn, K.W. Maxwell, Am. Zvonok, A. Makriyannis

Journal:

European Journal of Pain

Year:

2007

Language:

english

File:

PDF, 40 KB

english, 2007

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